Sua classifica??o dada pela detec??o na imunofluorescncia de anticorpos anti-membrana basal glomerular (Anti-MBG), imunocomplexos, ou padr?o pauci-imune. few reviews within the literature, highlighting the significance of its contribution and confirming towards the literature. Keywords: Lupus Erythematosus, Systemic; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Nefropatias; Glomerulonephritis Resumo A glomerulonefrite rapidamente progressiva uma emergncia mdica, com mortalidade em torno de 20%. caracterizada por glomerulonefrite com crescentes e perda progressiva da fun??o renal, hematria e proteinria. Sua classifica??o dada pela detec??o na imunofluorescncia de anticorpos anti-membrana basal glomerular (Anti-MBG), imunocomplexos, ou padr?o pauci-imune. Sua etiologia deve ser baseada em resultados clnicos, perfil imunolgico, idade, sexo e caractersticas histopatolgicas. Apresentamos o caso de uma mulher de 27 Angiotensin II human Acetate anos de idade com sintomas consistentes com uma glomerulonefrite rapidamente progressiva e achados de bipsia de uma nefropatia com padr?o full-house que evoluiu com desfecho fatal precoce. A associa??o de um padr?o full-house, que possui uma baixa incidncia, com um perfil autoimune em virtude de lpus eritematoso sistmico negativo torna este um caso raro. Foi diagnosticado vasculite associada ao ANCA com doen?a renal com padr?o full-house. Por se tratar de uma condi??o incomum com in 3% de apresenta??o e poucos registros na literatura, destacamos a importancia de seu relato e sua contribui??o em virtude de a literatura. Descritores: Lpus Eritematoso Sistmico, Vasculite Associada a Anticorpo Anticitoplasma de Neutrfilos, Nefropatias, Glomerulonefrite Intro Rapidly intensifying glomerulonephritis (RPGN) is really a medical crisis characterized by fast loss (times to weeks) of kidney function. It happens even more like a nephritic symptoms showing hypertension regularly, proteinuria within the non-nephrotic range, impaired renal function, and hematuria. The pathophysiology of the condition is dependant on immunopathological procedures that are categorized into 3 types: glomerulonephritis mediated by antibodies contrary to the glomerular cellar membrane (Goodpasture disease); glomerulonephritis mediated by immunocomplexes (systemic lupus erythematosus, post-streptococcal, Henoch-Schonlein purpura) and Pauci-immune glomerulonephritis (ANCA-positive vasculitis with specificity for proteinase 3 – PR3 or myeloperoxidase – MPO). The second option compromises little vessels, generating even more kidney harm in microscopic polyangiitis (MPA) and higher lung participation in granulomatosis with polyangiitis (GPA). Nevertheless, neither the organic bargain nor the positivity from the ANCAS can offer diagnostic certainty, due to the fact they could be positive in additional pathologies such as for example SLE, endocarditis, inflammatory colon disease, amongst others, and in healthy populations even. We present a complete case of an individual with RPGN and positive P-ANCA and renal biopsy, displaying crescentic glomerulonephritis having a “full-house” design in indirect immunofluorescence and adverse DES SLE autoimmune account, which is a unique association. Case explanation A 27 yr old woman lacking any important clinical background, shown in the Angiotensin II human Acetate er confirming 15 days of edema in the Angiotensin II human Acetate low oliguria and limbs evolution. She referred putting on weight within the last 15 times of 5 kilograms approximately. Upon physical exam, she offered blood circulation pressure in the number of hypertensive problems, bipalpebral edema, jugular engorgement, basal crackles both in lung bases, and stage II edema with fovea in every four limbs. The entrance test demonstrated metabolic acidosis with raised anion gap, bloodstream count number with leukocytosis, neutrophilia, normocytic normochromic anemia without transfusion requirements, electrolytes with serious hyperkalemia, KDIGO 3 severe kidney damage (Desk 1), and electrocardiographic adjustments of hyperkalemia. In her preliminary approach like a hypertensive crisis with a jeopardized kidney pitched against a nephritic symptoms, medical administration was began and, because of refractoriness, it had been made a decision to perform hemodialysis within the nephrology assistance. Further research with renal ultrasound demonstrated chronic parenchymal procedure with indications of exacerbation, the individual got improved phosphorus calcium mineral account with an increase of PTH also, autoimmune account with only 1 locating of positive P-ANCAS (1/160), and adverse infectious account (Desk 2). The medical evolution had continual signs.